Perfil químico, flavonoides totais, atividade antioxidante e citotóxica dos extratos de Guapira pernambucensis

Jéssica da Silva Xarifa Gomes; Kíssila Gomes Barreto; Carlos Roberto Ribeiro Matos; Leda Mathias

doi:10.19180/1809-2667.v21n12019p97-108

Chemical profile, total flavonoids, antioxidant and cytotoxic activity of the extracts of Guapira pernambucensis

Authors

Jéssica da Silva Xarifa Gomes Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ http://orcid.org/0000-0002-6173-0256
Kíssila Gomes Barreto Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ https://orcid.org/0000-0001-9172-540X
Carlos Roberto Ribeiro Matos Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ https://orcid.org/0000-0003-2953-0091
Leda Mathias Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ https://orcid.org/0000-0003-1023-5877

DOI:

https://doi.org/10.19180/1809-2667.v21n12019p97-108

Keywords:

Phytochemistry, Antioxidant potential, Artemia salina

Abstract

The leaves of the species Guapira pernambucensis were submitted to chemical profile analysis and evaluation of antioxidant and cytotoxic activities. The presence of triterpenes, steroids, alkaloids, flavonoids, proanthocyanidins and phenolics was identified. The antioxidant activity and flavonoid analysis showed an EC50 = 280.90 ± 1.15 ?g/mL and 20.4 ± 0.50 mg ER/g extract, respectively. The cytotoxicity against Artemia salina larvae presented an LD50 = 171 ?g/mL. The study showed a low antioxidant capacity, despite the presence of flavonoids, and a moderate cytotoxicity.

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Author Biographies

Jéssica da Silva Xarifa Gomes, Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ

Licenciada em Química pela Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF). Mestre em Ciências Naturais na Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) – Campos dos Goytacazes/RJ – Brasil. E-mail: jsxgomes@hotmail.com.
Kíssila Gomes Barreto, Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ

Mestre em Ciências Naturais pela Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) – Campos dos Goytacazes/RJ – Brasil. E-mail: kissila.barreto@hotmail.com.
Carlos Roberto Ribeiro Matos, Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ

Doutor em Química pelo Instituto de Química da Universidade Federal do Rio de Janeiro (UFRJ). Professor Associado da Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) – Campos dos Goytacazes/RJ – Brasil. E-mail: matos@uenf.br.
Leda Mathias, Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes/RJ

Doutora em Química de Produtos Naturais pela Universidade Federal do Rio de Janeiro (UFRJ). Professora da Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) – Campos dos Goytacazes/RJ – Brasil. E-mail: leddam8@gmail.com.

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Published

03-05-2019

Issue

Vol. 21 No. 1 (2019): Jan./Apr.

Section

Original articles

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How to Cite

GOMES, Jéssica da Silva Xarifa; BARRETO, Kíssila Gomes; MATOS, Carlos Roberto Ribeiro; MATHIAS, Leda. Chemical profile, total flavonoids, antioxidant and cytotoxic activity of the extracts of Guapira pernambucensis. Revista Vértices, [S. l.], v. 21, n. 1, p. 97–108, 2019. DOI: 10.19180/1809-2667.v21n12019p97-108. Disponível em: https://editoraessentia.iff.edu.br/index.php/vertices/article/view/12080.. Acesso em: 22 dec. 2024.